SCHEMBL7827488

SCHEMBL7827488

CCCOc1cccc2c1C(=N)NC2(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.35
PDK2 Q15119 1/20 0.35
CYP2A6 P11509 1/20 0.34
GCGR P47871 1/20 0.33
PRKCA P17252 6/20 0.32
TLR8 Q9NR97 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
GRM5 P41594 1/20 0.31
TP53 P04637 1/20 0.31
PDE7A Q13946 1/20 0.30
PDE7B Q9NP56 1/20 0.30
MAPT P10636 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
PDE5A O76074 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7829948 0.93 CYP1A2 (0.40) MCHR1PDK2PRKCATLR8CYP1A2
SCHEMBL7826806 0.91 PRKCA (0.42) MCHR1PRKCATLR8CYP1A2CYP2C9
SCHEMBL7830779 0.91 PRKCA (0.42) MCHR1PRKCATLR8CYP1A2CYP2C9
SCHEMBL7824104 0.90 PDK2 (0.43) PDK2CYP2A6TP53MAPTNPSR1
SCHEMBL7827247 0.89 PDK2 (0.36) MCHR1PDK2CYP2A6GCGRPRKCA
SCHEMBL7822891 0.82 CYP1A2 (0.38) MCHR1PDK2PRKCATLR8CYP1A2
SCHEMBL7825538 0.82 PDK2 (0.39) PDK2TP53MAPT
SCHEMBL7828606 0.80 PRKCA (0.40) MCHR1PDK2PRKCATLR8CYP1A2
SCHEMBL7827899 0.80 PRKCA (0.40) MCHR1PDK2PRKCATLR8CYP1A2
SCHEMBL7825899 0.80 PDE5A (0.35) MCHR1CYP2A6CYP1A2PDE7APDE7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed