Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL7835323 | 0.91 | ADRA1A (0.54) | HTR2ADRD4ADRA1AHTR1ADRD2 | |
| SCHEMBL7815509 | 0.85 | HTR2A (0.61) | HTR2ADRD4ADRA1AHTR1ADRD2 | |
| SCHEMBL7817256 | 0.84 | HTR2A (0.56) | HTR2ADRD4ADRA1AHTR1ADRD2 | |
| SCHEMBL8651520 | 0.83 | HTR2A (0.59) | HTR2ADRD4ADRA1AHTR1ADRD2 | |
| SCHEMBL4442569 | 0.83 | HTR1A (0.65) | HTR2ADRD4ADRA1AHTR1ADRD2 | |
| SCHEMBL9018059 | 0.82 | HTR2A (0.56) | HTR2ADRD4ADRA1AHTR1ADRD2 | |
| SCHEMBL4299920 | 0.81 | HTR2A (0.57) | HTR2ADRD4ADRA1AHTR1ADRD2 | |
| SCHEMBL7817436 | 0.81 | HTR2A (0.56) | HTR2ADRD4ADRA1AHTR1ADRD2 | |
| SCHEMBL4438394 | 0.80 | HTR2A (0.56) | HTR2ADRD4ADRA1AHTR1ADRD2 | |
| SCHEMBL9018113 | 0.80 | HTR2A (0.54) | HTR2ADRD4ADRA1AHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732332-B1 | Substituted benzothienylpiperazines, their use as medicaments, and processes for their preparation | AVENTIS PHARMA INC (US) | 2001-12-19 | — | — | EP | claimed |