Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MAOA | P21397 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.44 |
| ▸ | APEX1 | P27695 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825402 | 0.88 | CDC25B (0.46) | MAOAMAOBTTRCDC25BTOP2A | |
| SCHEMBL9197522 | 0.88 | MAPT (0.60) | MAPTMEN1KMT2AMAOAHPGD | |
| SCHEMBL7813936 | 0.83 | MAOA (0.49) | MAPTMEN1KMT2AMAOAHPGD | |
| SCHEMBL7819427 | 0.83 | MAOA (0.49) | MAPTMEN1KMT2AMAOAHPGD | |
| SCHEMBL3896954 | 0.82 | CSNK2A2 (0.54) | MAPTMEN1KMT2AMAOAHPGD | |
| SCHEMBL11863082 | 0.81 | MAPT (0.76) | MAPTMEN1KMT2AMAOAHPGD | |
| SCHEMBL7809872 | 0.74 | MEN1 (0.39) | MAPTMEN1KMT2AMAOAHPGD | |
| SCHEMBL3897351 | 0.72 | MAOA (0.73) | MAPTMEN1KMT2AMAOAHPGD | |
| SCHEMBL6674009 | 0.72 | CSNK2A2 (0.44) | MAPTMEN1KMT2AMAOAHPGD | |
| SCHEMBL27680313 | 0.72 | MAPT (0.61) | MAPTMEN1KMT2AMAOAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750619-B1 | HETERO-ANNULATED INDAZOLES | NOVUSPHARMA SPA (IT) | 2001-05-30 | — | — | EP | disclosed |
| US-5596097-A | ANTITUMOR AGENTS | THE UNIVERSITY OF VERMONT (US) | 1997-01-21 | — | — | US | disclosed |
| WO-1995024407-A1 | HETERO-ANNULATED INDAZOLES | BOEHRINGER MANNHEIM ITALIA, S.P.A. (IT) | 1995-09-14 | — | — | WO | disclosed |