Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347935 | 0.89 | TSHR (0.59) | TSHRALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL11316296 | 0.87 | PKM (0.50) | TSHRPKMALDH1A1KMT2APOLB | |
| SCHEMBL145816 | 0.84 | KDM4E (0.52) | TSHRPKMALDH1A1KDM4ETDP1 | |
| SCHEMBL11042208 | 0.82 | ALDH1A1 (0.49) | TSHRPKMALDH1A1KMT2APOLB | |
| SCHEMBL9651424 | 0.82 | PKM (0.47) | TSHRPKMALDH1A1KMT2AKDM4E | |
| SCHEMBL10387706 | 0.82 | PKM (0.47) | TSHRPKMALDH1A1KMT2AKDM4E | |
| SCHEMBL3597707 | 0.82 | TSHR (0.62) | TSHRALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL29795771 | 0.82 | TSHR (0.62) | TSHRALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL19064023 | 0.81 | PKM (0.46) | TSHRPKMALDH1A1KMT2AKDM4E | |
| SCHEMBL31184710 | 0.81 | PKM (0.46) | TSHRPKMALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |