Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TPMT | P51580 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29795771 | 0.89 | TSHR (0.62) | TSHRALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL7824318 | 0.89 | TSHR (0.53) | TSHRALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL3597707 | 0.89 | TSHR (0.62) | TSHRALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL9315175 | 0.87 | TSHR (0.84) | TSHRALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL30218255 | 0.84 | KMT2A (0.60) | TSHRALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL1812368 | 0.83 | MAPK1 (0.48) | TSHRALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL1813258 | 0.82 | ALDH1A1 (0.47) | TSHRALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL6455620 | 0.82 | SMN1; SMN2 (0.57) | TSHRALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL15299306 | 0.82 | TSHR (0.49) | TSHRALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL1811071 | 0.82 | ALDH1A1 (0.47) | TSHRALDH1A1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10546303-B2 | Optically visible carbon nanotube with nanocrystals decoration as unique ID | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2020-01-28 | — | — | US | claimed |
| US-20180276682-A1 | Optically Visible Carbon Nanotube with Nanocrystals Decoration as Unique ID | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-09-27 | — | — | US | claimed |
| CN-101861303-A | Glycogen phosphorylase inhibitor compound and its pharmaceutical composition | SMITHKLINE BEECHAM CORP | 2010-10-13 | — | — | CN | claimed |
| US-20100234433-A1 | GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | GLAXOSMITHKLINE LLC | 2010-09-16 | — | — | US | claimed |
| EP-2197845-A1 | GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | GlaxoSmithKline LLC (US) | 2010-06-23 | — | — | EP | claimed |
| WO-2009045831-A1 | GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | claimed |
| CN-119100946-A | Synthesis method of key intermediate of rilpivirine | 石家庄龙泽制药股份有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-111943153-B | Method and system for treating nitric acid containing high boiling point organic matter, and method and apparatus for preparing substituted nitrobenzoic acid | 山东友道化学有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-111620397-B | Treatment system and treatment method for nitric acid-containing system | 山东友道化学有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-111792631-B | Device and method for treating nitric acid containing high-boiling-point organic matters | 山东友道化学有限公司 | 2023-08-18 | — | — | CN | disclosed |
| US-11584765-B2 | Polycyclic amines as sigma receptor modulators | Ecstasy LLC (US) | 2023-02-21 | — | — | US | disclosed |
| CN-110662541-B | Polycyclic amines as opioid receptor modulators | 王晓冬 | 2023-02-10 | — | — | CN | disclosed |
| US-20220411442-A1 | POLYCYCLIC AMINES AS OPIOID RECEPTOR MODULATORS | Ecstasy LLC | 2022-12-29 | — | — | US | disclosed |
| EP-0211568-A1 | Anticonvulsant agents | ELI LILLY AND COMPANY (US) | 1987-02-25 | — | — | EP | disclosed |
| EP-0187231-A2 | Amino phenyl benzothiazoles | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |
| EP-0035393-A1 | Poultry feeds containing and methods of using anovulatory compounds, and novel anovulatory imidazolines | MERCK & CO. INC. (US) | 1981-09-09 | — | — | EP | disclosed |
| US-4287201-A | CONTAINING A 2-(SUBSTITUTED PHENYLIMINO)IMIDAZOLIDINE COMPOUND | MERCK & CO., INC. (US) | 1981-09-01 | — | — | US | disclosed |
| EP-0001246-B1 | PREPARATION OF 2-(3'- OR 4'-AMINOPHENYL)-5(OR 6)-AMINOBENZIMIDAZOLES | CASSELLA Aktiengesellschaft (DE) | 1981-02-25 | — | — | EP | disclosed |
| US-4192947-A | REACTING DIAMINO NITROBENZENE WITH NITROBENZOYL CHLORIDE, CYCLIZING ANILIDE IN AQUEOUS ALKALI, REDUCING NITRO GROUPS WITH SULFIDE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-03-11 | — | — | US | disclosed |
| EP-0001246-A1 | Preparation of 2-(3'- or 4'-aminophenyl)-5(or 6)-aminobenzimidazoles | CASSELLA Aktiengesellschaft (DE) | 1979-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584765-B2 | Polycyclic amines as sigma receptor modulators | OPRM1, SIGMAR1, OPRK1 | TSHR 845/4885ALDH1A1 1039/4885KMT2A 1818/4885 |
| US-20100234433-A1 | GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | PYGM, PYGL, G6PC1 | TSHR 4714/4885ALDH1A1 3219/4885KMT2A 2279/4885 |
| US-20220411442-A1 | POLYCYCLIC AMINES AS OPIOID RECEPTOR MODULATORS | OPRM1, OPRL1, OPRK1 | TSHR 829/4885ALDH1A1 825/4885KMT2A 1414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.