Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | GRK2 | P25098 | 1/20 | 0.69 |
| ▸ | CASP6 | P55212 | 1/20 | 0.69 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.69 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | FNTA | P49354 | 1/20 | 0.65 |
| ▸ | FNTB | P49356 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19420106 | 0.84 | HTT (0.72) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL7823539 | 0.83 | MAPT (1.00) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL3917111 | 0.83 | RAB9A (1.00) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL889076 | 0.83 | HTT (0.54) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL7823332 | 0.81 | TDP1 (0.73) | HTTSMN1; SMN2POLBLMNATDP1 | |
| SCHEMBL23509616 | 0.80 | RAB9A (0.64) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL12218175 | 0.80 | POLB (0.70) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL19473737 | 0.80 | RAB9A (0.64) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL31335388 | 0.80 | RAB9A (0.72) | RAB9AHTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL7828785 | 0.80 | HTT (0.71) | RAB9AHTTKDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |