Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.57 |
| ▸ | FPR2 | P25090 | 4/20 | 0.50 |
| ▸ | FPR1 | P21462 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | FPR3 | P25089 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | GRK2 | P25098 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23509616 | 1.00 | RAB9A (0.64) | RAB9ANPC1KMT2AEPHX1MEN1 | |
| SCHEMBL19473756 | 1.00 | RAB9A (0.64) | RAB9ANPC1KMT2AEPHX1MEN1 | |
| SCHEMBL19473738 | 0.99 | RAB9A (0.67) | RAB9ANPC1KMT2AEPHX1MEN1 | |
| SCHEMBL23509611 | 0.99 | RAB9A (0.67) | RAB9ANPC1KMT2AEPHX1MEN1 | |
| SCHEMBL19473762 | 0.97 | KMT2A (0.60) | RAB9ANPC1KMT2AEPHX1MEN1 | |
| SCHEMBL19473763 | 0.85 | EPHX1 (0.51) | RAB9ANPC1KMT2AEPHX1MEN1 | |
| SCHEMBL5950145 | 0.83 | GRK2 (0.70) | RAB9ANPC1KMT2AEPHX1MEN1 | |
| SCHEMBL85562 | 0.82 | RAB9A (0.62) | RAB9ANPC1KMT2AEPHX1MEN1 | |
| SCHEMBL76526 | 0.82 | RAB9A (0.62) | RAB9ANPC1KMT2AEPHX1MEN1 | |
| SCHEMBL19473764 | 0.81 | RAB9A (0.50) | RAB9ANPC1KMT2AEPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11286234-B2 | Phenyl urea derivatives as N-formyl peptide receptor modulators | ALLERGAN, INC. (US) | 2022-03-29 | — | — | US | disclosed |
| US-20210179550-A1 | PHENYL UREA DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN, INC. | 2021-06-17 | — | — | US | disclosed |
| WO-2017180323-A1 | PHENYL UREA DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2017-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11286234-B2 | Phenyl urea derivatives as N-formyl peptide receptor modulators | FPR1, FPR2, FPR3 | RAB9A 4635/4885NPC1 2028/4885KMT2A 4689/4885 |
| US-20210179550-A1 | PHENYL UREA DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR MODULATORS | FPR1, FPR2, FPR3 | RAB9A 4635/4885NPC1 2028/4885KMT2A 4689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.