Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NEU2 | Q9Y3R4 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828982 | 0.89 | MAPT (0.30) | MAPT | |
| SCHEMBL7828985 | 0.89 | MAPT (0.30) | MAPT | |
| SCHEMBL7831548 | 0.88 | NFKB1 (0.31) | NFKB1NFKB2RELA | |
| SCHEMBL7827514 | 0.88 | CTSK (0.34) | CTSK | |
| SCHEMBL7827619 | 0.86 | — | — | |
| SCHEMBL7827621 | 0.86 | — | — | |
| SCHEMBL7827511 | 0.86 | — | — | |
| SCHEMBL7837385 | 0.86 | — | — | |
| SCHEMBL7827371 | 0.85 | NEU2 (0.34) | MAPTCTSSCTSKKDM4EALDH1A1 | |
| SCHEMBL7827367 | 0.84 | NEU2 (0.48) | LMNANEU2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833825-B1 | 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES | BIOTA SCIENT MANAGEMENT (AU) | 2001-09-26 | — | — | EP | disclosed |
| US-5990156-A | 6-Carboxamido dihydropyran derivatives | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 1999-11-23 | — | — | US | disclosed |
| EP-0833825-A4 | 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES | BIOTA SCIENT MANAGEMENT (AU) | 1998-10-07 | — | — | EP | disclosed |
| EP-0833825-A1 | 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996036628-A1 | 6-CARBOXAMIDO DIHYDROPYRAN DERIVATIVES | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 1996-11-21 | — | — | WO | disclosed |