Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831628 | 0.90 | ALK (0.38) | PDE3BPDE3AP2RY12CTSVCTSL | |
| SCHEMBL7826811 | 0.90 | ALDH1A1 (0.40) | PDE3BPDE3AP2RY12CTSVCTSL | |
| SCHEMBL7823420 | 0.88 | DYRK1A (0.44) | PDE3BPDE3AP2RY12ALDH1A1HPGD | |
| SCHEMBL7832144 | 0.85 | CTSV (0.42) | CTSVCTSLALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7827211 | 0.85 | HSD17B10 (0.51) | PDE3BPDE3ACTSVCTSLALDH1A1 | |
| SCHEMBL7816507 | 0.84 | POLB (0.45) | ALDH1A1HPGDMAPTKDM4EGAA | |
| SCHEMBL7826727 | 0.84 | CA12 (0.42) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL7829082 | 0.84 | CTSV (0.44) | CTSVCTSLALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7824749 | 0.83 | CTSV (0.60) | CTSVCTSLALDH1A1HPGDKDM4E | |
| SCHEMBL7824605 | 0.83 | CTSV (0.43) | CTSVCTSLDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |