Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 5/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MDH2 | P40926 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824605 | 0.97 | CTSV (0.43) | CTSVCTSLMAOADYRK1ACYP2D6 | |
| SCHEMBL7816229 | 0.89 | MAOA (0.47) | CTSVCTSLMAOA | |
| SCHEMBL7826517 | 0.89 | MAOA (0.52) | CTSVCTSLMAOADYRK1ACYP2D6 | |
| SCHEMBL7827564 | 0.88 | MAOA (0.47) | CTSVCTSLMAOA | |
| SCHEMBL7824749 | 0.88 | CTSV (0.60) | CTSVCTSLMAOAALDH1A1HPGD | |
| SCHEMBL7831835 | 0.88 | CTSV (0.40) | CTSVCTSLMAOACYP2D6ALDH1A1 | |
| SCHEMBL7827211 | 0.85 | HSD17B10 (0.51) | CTSVCTSLNPC1ALDH1A1HPGD | |
| SCHEMBL7824709 | 0.84 | PDE2A (0.41) | CTSVCTSLDYRK1AALDH1A1HPGD | |
| SCHEMBL7826175 | 0.84 | MAOA (0.54) | MAOADYRK1AALDH1A1SMN1; SMN2 | |
| SCHEMBL7831263 | 0.83 | ACHE (0.52) | MAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |