Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | CASP1 | P29466 | 2/20 | 0.61 |
| ▸ | CASP7 | P55210 | 2/20 | 0.61 |
| ▸ | CDC42 | P60953 | 2/20 | 0.43 |
| ▸ | RAC1 | P63000 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820317 | 0.87 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL17539940 | 0.83 | ALDH1A1 (0.76) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL7826567 | 0.80 | MAPT (0.45) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL7823305 | 0.79 | MAPT (0.68) | KDM4EALDH1A1HPGDMEN1MAPT | |
| Hydrochloric Acid SCHEMBL7820109 | 0.79 | MAPT (0.44) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL278878 | 0.78 | KDM4E (0.97) | KDM4EALDH1A1HPGDMEN1MAPT | |
| Hydrochloric Acid SCHEMBL3320097 | 0.76 | KDM4E (1.00) | KDM4EALDH1A1HPGDMEN1MAPT | |
| Water SCHEMBL4022544 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL29502920 | 0.74 | MAPT (0.59) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL17539939 | 0.74 | KDM4E (0.67) | KDM4EALDH1A1HPGDMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888346-B1 | CORALYNE ANALOGS AS TOPOISOMERASE INHIBITORS | UNIV RUTGERS (US) | 2001-06-06 | — | — | EP | claimed |