Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7820109 | 0.99 | MAPT (0.44) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL29502920 | 0.84 | MAPT (0.59) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7824722 | 0.80 | KDM4E (0.61) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7821022 | 0.77 | MAPT (0.65) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL7812760 | 0.76 | MAPT (0.64) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL13349142 | 0.74 | MAPT (0.46) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL7826957 | 0.73 | CYP3A4 (0.68) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7820317 | 0.72 | ALDH1A1 (0.47) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL10132560 | 0.70 | BAD (0.76) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| Bromide SCHEMBL11728626 | 0.70 | IDO1 (0.44) | MAPTMEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888346-B1 | CORALYNE ANALOGS AS TOPOISOMERASE INHIBITORS | UNIV RUTGERS (US) | 2001-06-06 | — | — | EP | claimed |