Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529361 | 0.85 | ESR1 (0.46) | TSPOALDH1A1ESR1GPBAR1RAB9A | |
| SCHEMBL11410673 | 0.85 | TSPO (0.45) | TSPOALDH1A1ESR1GPBAR1RAB9A | |
| SCHEMBL7816426 | 0.81 | TSPO (0.47) | TSPOESR1GPBAR1POLBSMN1; SMN2 | |
| SCHEMBL12574308 | 0.80 | TSPO (0.50) | TSPOALDH1A1GPBAR1RAB9APOLB | |
| SCHEMBL7831271 | 0.80 | ALDH1A1 (0.43) | ALDH1A1POLBSMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL13263641 | 0.80 | CYP1A2 (0.47) | ALDH1A1ESR1L3MBTL1LMNA | |
| SCHEMBL13041475 | 0.80 | ESR1 (0.42) | TSPOALDH1A1ESR1RAB9ASMN1; SMN2 | |
| SCHEMBL8779753 | 0.79 | TSPO (0.53) | TSPOALDH1A1GPBAR1POLBSMN1; SMN2 | |
| SCHEMBL2536563 | 0.79 | TSPO (0.67) | TSPOALDH1A1ESR1GPBAR1RAB9A | |
| SCHEMBL13233265 | 0.78 | L3MBTL1 (0.41) | TSPOALDH1A1ESR1GPBAR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |