Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810677 | 0.83 | — | — | |
| SCHEMBL8784394 | 0.81 | HRH4 (0.35) | — | |
| SCHEMBL8647402 | 0.77 | PTGES (0.30) | — | |
| SCHEMBL7810607 | 0.74 | CYP19A1 (0.41) | — | |
| SCHEMBL8784365 | 0.71 | HRH4 (0.34) | — | |
| SCHEMBL7466499 | 0.70 | HRH4 (0.35) | — | |
| SCHEMBL7820148 | 0.70 | — | — | |
| SCHEMBL8649343 | 0.69 | HRH4 (0.37) | — | |
| SCHEMBL7819812 | 0.69 | GBA1 (0.33) | — | |
| SCHEMBL8784616 | 0.69 | TLR8 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781279-B1 | QUINOXALINEDIONE NMDA RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 2001-06-13 | — | — | EP | disclosed |
| US-5783572-A | TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER INC. (US) | 1998-07-21 | — | — | US | disclosed |
| EP-0781279-A1 | QUINOXALINEDIONE NMDA RECEPTOR ANTAGONISTS | Pfizer Limited (GB) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008485-A1 | QUINOXALINEDIONE NMDA RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1996-03-21 | — | — | WO | disclosed |