Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | GCKR | Q14397 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | UQCRB | P14927 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12091515 | 0.81 | ENPP2 (0.41) | ALDH1A1SMN1; SMN2LOXL2 | |
| SCHEMBL3701877 | 0.79 | KDM4E (0.57) | KDM4ENAPRTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18379351 | 0.79 | CA2 (0.50) | TDP1TSHR | |
| SCHEMBL8438731 | 0.78 | KDM4E (0.65) | KDM4ENAPRTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5077872 | 0.78 | KDM4E (0.55) | KDM4ENAPRTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL22068923 | 0.78 | GAA (0.44) | KDM4ELMNAALDH1A1TDP1MAPT | |
| Hydrochloric Acid SCHEMBL27930121 | 0.78 | KDM4E (0.55) | KDM4ENAPRTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3162360 | 0.77 | KDM4E (0.59) | KDM4ENAPRTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL12313525 | 0.76 | CCR1 (0.61) | KDM4ENAPRTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL17688866 | 0.76 | HSD17B10 (0.49) | KDM4ELMNAALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |