Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701877 | 0.98 | KDM4E (0.57) | KDM4ETRPV4KCNH2MAP4K4PIK3CA | |
| Hydrochloric Acid SCHEMBL27930121 | 0.96 | KDM4E (0.55) | KDM4ETRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL244098 | 0.78 | TRPV4 (0.52) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL18231250 | 0.78 | KCNH2 (0.55) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL2169084 | 0.78 | TRPV4 (0.52) | KDM4ETRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL7825110 | 0.78 | KDM4E (0.57) | KDM4ENAPRTLMNAALDH1A1TSHR | |
| SCHEMBL5077871 | 0.78 | TRPV4 (0.52) | KDM4ETRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL29948975 | 0.78 | TRPV4 (0.52) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL30845950 | 0.78 | TRPV4 (0.52) | KDM4ETRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL8438731 | 0.76 | KDM4E (0.65) | KDM4ENAPRTLMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497374-B1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GEN ELECTRIC (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7244778-B2 | Filler reinforced polyether imide resin composition and molded article thereof | GENERAL ELECTRIC COMPANY (US) | 2007-07-17 | — | — | US | disclosed |
| US-20050131105-A1 | Filler reinforced polyether imide resin composition and molded article thereof | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2005-06-16 | — | — | US | disclosed |