Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683523 | 0.72 | DPP4 (0.37) | KDM4ELMNAHTTTSHRMAPT | |
| SCHEMBL3145084 | 0.71 | RAB9A (0.53) | KDM4ELMNAHTTTSHRMAPT | |
| SCHEMBL7673942 | 0.69 | CYP2A6 (0.44) | KDM4ELMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL1282008 | 0.69 | CCR1 (0.75) | KDM4ELMNAHTTTSHRMAPT | |
| SCHEMBL30184687 | 0.69 | CCR1 (0.75) | KDM4ELMNAHTTTSHRMAPT | |
| SCHEMBL12853981 | 0.66 | LMNA (0.68) | KDM4ELMNAHTTTSHRMAPT | |
| SCHEMBL8544603 | 0.65 | PDE10A (0.57) | KDM4ELMNAHTTTSHRMAPT | |
| SCHEMBL28008054 | 0.63 | KDM4E (0.58) | KDM4ELMNAHTTTSHRMAPT | |
| SCHEMBL2672167 | 0.63 | KDM4E (0.51) | KDM4ELMNAHTTTSHRMAPT | |
| SCHEMBL17334526 | 0.63 | CCR1 (0.62) | KDM4ELMNAHTTTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885212-B1 | QUINOXALINEDIONES | PFIZER RES AND BR DEV COMPANY (IE) | 2001-11-14 | — | — | EP | claimed |