Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | TTPA | P49638 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838544 | 0.92 | MEN1 (0.50) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL7833225 | 0.89 | KMT2A (0.47) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL7833222 | 0.85 | MAPT (0.43) | MEN1KMT2ATTPAALOX5LMNA | |
| SCHEMBL7835312 | 0.82 | TTPA (0.55) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL7825643 | 0.77 | MAPT (0.45) | MEN1KMT2ATTPAALOX5LMNA | |
| SCHEMBL7855561 | 0.76 | ATM (0.40) | MEN1KMT2APDE4APDE3ALMNA | |
| SCHEMBL7826448 | 0.75 | MAPT (0.43) | MEN1KMT2ATTPAALOX5LMNA | |
| SCHEMBL7834104 | 0.75 | MAPT (0.43) | MEN1KMT2ATTPAALOX5LMNA | |
| SCHEMBL14168733 | 0.74 | MEN1 (0.64) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8376060 | 0.74 | MEN1 (0.64) | MEN1KMT2APDE4APDE3ATTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844245-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-05-09 | — | — | EP | disclosed |
| US-5889045-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |
| EP-0844245-A1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-27 | — | — | EP | disclosed |