Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | TTPA | P49638 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825367 | 0.92 | MEN1 (0.48) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL7833225 | 0.91 | KMT2A (0.47) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL7825643 | 0.85 | MAPT (0.45) | MEN1KMT2ATTPAALOX5LMNA | |
| SCHEMBL7825046 | 0.81 | TTPA (0.56) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9094867 | 0.80 | MEN1 (0.52) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9094873 | 0.80 | MEN1 (0.52) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL7855561 | 0.77 | ATM (0.40) | MEN1KMT2APDE4APDE3AALDH1A1 | |
| SCHEMBL7826448 | 0.77 | MAPT (0.43) | MEN1KMT2ATTPAALOX5LMNA | |
| SCHEMBL7834104 | 0.77 | MAPT (0.43) | MEN1KMT2ATTPAALOX5LMNA | |
| SCHEMBL9312862 | 0.77 | MEN1 (0.52) | MEN1KMT2APDE4APDE3ATTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844245-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-05-09 | — | — | EP | disclosed |
| US-5889045-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |
| EP-0844245-A1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-27 | — | — | EP | disclosed |