Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833225 | 0.86 | KMT2A (0.47) | ATMPOLBSMN1; SMN2LMNACA1 | |
| SCHEMBL7838544 | 0.77 | MEN1 (0.50) | LMNAKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL7825367 | 0.76 | MEN1 (0.48) | SMN1; SMN2LMNAKMT2AMEN1PDE4A | |
| SCHEMBL7844906 | 0.74 | TTPA (0.40) | SMN1; SMN2CYP1A2 | |
| SCHEMBL7844737 | 0.73 | TTPA (0.39) | CYP1A2 | |
| SCHEMBL7825643 | 0.72 | MAPT (0.45) | LMNAKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL7826448 | 0.70 | MAPT (0.43) | LMNAKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL7833222 | 0.70 | MAPT (0.43) | LMNAKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL7834104 | 0.70 | MAPT (0.43) | LMNAKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL7836807 | 0.70 | TTPA (0.53) | POLBSMN1; SMN2LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844245-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-05-09 | — | — | EP | disclosed |
| US-5889045-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |
| EP-0844245-A1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-27 | — | — | EP | disclosed |