Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068001 | 0.90 | ALDH1A1 (0.43) | KMT2AMEN1HSD17B10HPGDALDH1A1 | |
| SCHEMBL7816147 | 0.89 | PTGDR2 (0.42) | KMT2AMEN1HSD17B10HPGDALDH1A1 | |
| SCHEMBL7826196 | 0.89 | SLC5A1 (0.43) | KMT2AMEN1HSD17B10HPGDALDH1A1 | |
| SCHEMBL8057450 | 0.87 | ALDH1A1 (0.42) | KMT2AMEN1HSD17B10HPGDALDH1A1 | |
| SCHEMBL7823983 | 0.85 | LMNA (0.45) | KMT2AMEN1HSD17B10HPGDALDH1A1 | |
| SCHEMBL7831857 | 0.84 | SLC5A1 (0.43) | KMT2AMEN1HSD17B10HPGDALDH1A1 | |
| SCHEMBL7816556 | 0.84 | LMNA (0.44) | KMT2AMEN1HSD17B10HPGDALDH1A1 | |
| SCHEMBL7827659 | 0.83 | SLC5A1 (0.43) | KMT2AMEN1HSD17B10HPGDALDH1A1 | |
| SCHEMBL7816052 | 0.83 | SLC5A1 (0.41) | KMT2AMEN1HSD17B10HPGDALDH1A1 | |
| SCHEMBL7827608 | 0.83 | SLC5A1 (0.41) | KMT2AMEN1HSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |