Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 11/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067016 | 0.91 | KMT2A (0.43) | AKR1C3KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL7827515 | 0.89 | KMT2A (0.42) | AKR1C3KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL7825441 | 0.89 | KMT2A (0.43) | PTGDR2KMT2AALDH1A1HPGDSNCA | |
| SCHEMBL8067988 | 0.88 | MKNK2 (0.43) | PTGDR2AKR1C3KMT2AALDH1A1HPGD | |
| SCHEMBL7823440 | 0.85 | UCHL1 (0.41) | AKR1C3KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL7816556 | 0.84 | LMNA (0.44) | PTGDR2AKR1C3KMT2AALDH1A1HPGD | |
| SCHEMBL7826821 | 0.84 | UCHL1 (0.40) | AKR1C3KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL7823983 | 0.84 | LMNA (0.45) | PTGDR2AKR1C3KMT2AALDH1A1HPGD | |
| SCHEMBL7827030 | 0.84 | UCHL1 (0.42) | AKR1C3KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL7827496 | 0.83 | MAPT (0.39) | KMT2AALDH1A1HPGDMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |