Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559528 | 0.81 | CA2 (0.43) | CA2CA5ADRD3ALDH1A1HPGD | |
| SCHEMBL14105799 | 0.66 | GAA (0.57) | ALDH1A1HPGDKDM4EGAASMN1; SMN2 | |
| SCHEMBL17287663 | 0.64 | CA2 (0.48) | CA2CA5ADRD3ALDH1A1HPGD | |
| SCHEMBL11450799 | 0.64 | CA2 (0.45) | CA2CA5ADRD3ALDH1A1HPGD | |
| SCHEMBL6940152 | 0.64 | CA2 (0.50) | CA2CA5AALDH1A1HPGDGAA | |
| SCHEMBL11458474 | 0.63 | CA2 (0.41) | CA2CA5ADRD3ALDH1A1HPGD | |
| SCHEMBL28698687 | 0.63 | CA2 (0.50) | CA2CA5ADRD3ALDH1A1HPGD | |
| SCHEMBL11260239 | 0.62 | ALDH1A1 (0.42) | CA2CA5AALDH1A1HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL6558668 | 0.61 | CA2 (0.37) | CA2CA5ADRD3ALDH1A1HPGD | |
| SCHEMBL11258896 | 0.61 | CA2 (0.42) | CA2CA5ADRD3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |