Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11669795 | 0.88 | CA2 (0.37) | ALDH1A1CA2STSCA12BCHE | |
| SCHEMBL19308105 | 0.85 | CA2 (0.42) | ALDH1A1CA2CA5AHPGDALPL | |
| SCHEMBL11669133 | 0.85 | RAB9A (0.40) | ALDH1A1CA2GAAMAPTLMNA | |
| SCHEMBL9619914 | 0.85 | HSD11B1 (0.39) | CA2 | |
| SCHEMBL11260755 | 0.83 | CA2 (0.39) | ALDH1A1CA2CA5AHPGDALPL | |
| SCHEMBL11806875 | 0.82 | ACHE (0.34) | ALDH1A1HPGDLMNAHTTSTS | |
| SCHEMBL11269387 | 0.82 | CA2 (0.39) | ALDH1A1CA2CA5AHPGDALPL | |
| SCHEMBL11269026 | 0.82 | CA2 (0.39) | ALDH1A1CA2CA5AHPGDALPL | |
| SCHEMBL11257436 | 0.81 | ALDH1A1 (0.39) | ALDH1A1CA2CA5AHPGDALPL | |
| SCHEMBL11812672 | 0.79 | KCNE1 (0.32) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4345932-A | BENZOFURANYL ESTERS | FISONS LIMITED (GB) | 1982-08-24 | — | — | US | disclosed |
| US-4157255-A | 2-AMINO-BENZOFURAN-2-YL METHANE SULFONATE | FISONS LIMITED (GB) | 1979-06-05 | — | — | US | disclosed |
| US-4120871-A | HERBICIDES, PLANT GROWTH REGULATORS | FISONS LIMITED (GB) | 1978-10-17 | — | — | US | disclosed |