Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL7825607 | 0.76 | ABCC1 (0.57) | ALDH1A1MAPK1L3MBTL1HPGDNPC1 | |
| SCHEMBL11356974 | 0.74 | ALDH1A1 (0.75) | ALDH1A1MAPK1HPGDNPC1KMT2A | |
| SCHEMBL21616114 | 0.73 | ALDH1A1 (0.64) | ALDH1A1MAPK1HPGDNPC1KMT2A | |
| SCHEMBL21612947 | 0.71 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1HPGDNPC1 | |
| SCHEMBL11324603 | 0.70 | AIP (0.66) | ALDH1A1MAPK1L3MBTL1HPGDNPC1 | |
| SCHEMBL14680529 | 0.69 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1HPGDNPC1 | |
| SCHEMBL20922444 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1HPGDKMT2A | |
| SCHEMBL34468550 | 0.68 | ALDH1A1 (0.69) | ALDH1A1MAPK1L3MBTL1HPGDNPC1 | |
| SCHEMBL10451484 | 0.65 | ALDH1A1 (0.51) | ALDH1A1MAPK1HPGDNPC1MAPT | |
| SCHEMBL25475532 | 0.64 | TDP1 (0.39) | ALDH1A1MAPK1HPGDNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |