Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.81 |
| ▸ | MEN1 | O00255 | 6/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 0.81 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2947496 | 0.86 | MEN1 (0.79) | KMT2AMEN1POLBHPGDALDH1A1 | |
| SCHEMBL740618 | 0.84 | HPGD (0.74) | KMT2AMEN1POLBHPGDALDH1A1 | |
| SCHEMBL14119591 | 0.82 | ALDH1A1 (1.00) | KMT2AMEN1POLBHPGDALDH1A1 | |
| SCHEMBL5422115 | 0.82 | MAPT (0.74) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL28584650 | 0.79 | MEN1 (0.73) | KMT2AMEN1POLBHPGDALDH1A1 | |
| SCHEMBL13856491 | 0.79 | MAPT (1.00) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL4295568 | 0.78 | HIF1A (0.73) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL108275 | 0.77 | HPGD (0.64) | KMT2AMEN1POLBHPGDALDH1A1 | |
| SCHEMBL1734842 | 0.77 | NOTUM (0.81) | KMT2AMEN1POLBHPGDALDH1A1 | |
| SCHEMBL5698772 | 0.76 | MEN1 (0.67) | KMT2AMEN1HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |