Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826330 | 1.00 | MAPT (0.46) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10998038 | 0.79 | MAPT (0.50) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10998037 | 0.79 | MAPT (0.50) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7825843 | 0.72 | CA2 (0.39) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14435900 | 0.69 | ALDH1A1 (0.48) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10621154 | 0.68 | ALDH1A1 (0.57) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10621158 | 0.68 | ALDH1A1 (0.57) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL52224 | 0.68 | RAB9A (0.76) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL29554643 | 0.68 | RAB9A (0.76) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3777551 | 0.68 | RAB9A (0.76) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |