Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 9/20 | 0.80 |
| ▸ | CMA1 | P23946 | 8/20 | 0.80 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.80 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.80 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836801 | 0.89 | CTSG (0.64) | CTSGCMA1PRSS1CTRB1S1PR4 | |
| SCHEMBL7837287 | 0.89 | PRSS1 (0.64) | CTSGCMA1PRSS1CTRB1MEN1 | |
| SCHEMBL7826107 | 0.87 | PRSS1 (0.62) | CTSGCMA1PRSS1CTRB1S1PR4 | |
| SCHEMBL7836741 | 0.87 | PRSS1 (0.62) | CTSGCMA1PRSS1CTRB1S1PR4 | |
| SCHEMBL7836199 | 0.87 | CTSG (0.65) | CTSGCMA1PRSS1CTRB1S1PR4 | |
| SCHEMBL7835567 | 0.84 | CTSG (0.58) | CTSGCMA1PRSS1CTRB1S1PR4 | |
| SCHEMBL7835767 | 0.81 | PRSS1 (0.56) | CTSGCMA1PRSS1CTRB1S1PR4 | |
| SCHEMBL7834156 | 0.79 | CTSG (0.56) | CTSGCMA1PRSS1CTRB1S1PR4 | |
| SCHEMBL7837407 | 0.78 | PRSS1 (0.54) | CTSGCMA1PRSS1CTRB1S1PR4 | |
| SCHEMBL7825623 | 0.78 | CTSG (0.61) | CTSGCMA1PRSS1CTRB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORP (JP) | 2001-09-19 | — | — | EP | disclosed |
| US-5866592-A | Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same | NIPPON STEEL CORPORATION (JP) | 1999-02-02 | — | — | US | disclosed |