SCHEMBL645648

SCHEMBL645648

Cc1cc(C=O)c(C)n1-c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 5/20 0.68
L3MBTL1 Q9Y468 5/20 0.68
CTDSP1 Q9GZU7 3/20 0.68
TDP1 Q9NUW8 3/20 0.68
APEX1 P27695 2/20 0.68
ALDH1A1 P00352 15/20 0.62
LMNA P02545 5/20 0.62
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
CASP6 P55212 2/20 0.61
KDM4E B2RXH2 1/20 0.61
HTT P42858 1/20 0.61
MAPT P10636 5/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
MITF O75030 1/20 0.60
PLA2G1B P04054 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
ATG4B Q9Y4P1 1/20 0.60
CYP1A2 P05177 2/20 0.58
CYP2C9 P11712 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17802297 0.85 ALDH1A1 (0.65) POLBL3MBTL1CTDSP1TDP1APEX1
SCHEMBL12222500 0.84 POLB (0.67) POLBL3MBTL1CTDSP1TDP1APEX1
SCHEMBL21225472 0.82 ALDH1A1 (0.62) POLBL3MBTL1CTDSP1TDP1APEX1
SCHEMBL21225466 0.82 ALDH1A1 (0.61) POLBL3MBTL1CTDSP1TDP1APEX1
SCHEMBL7825875 0.82 POLB (0.75) POLBL3MBTL1CTDSP1TDP1APEX1
SCHEMBL645577 0.81 ALDH1A1 (0.60) POLBL3MBTL1CTDSP1TDP1APEX1
SCHEMBL15331958 0.81 POLB (1.00) POLBL3MBTL1CTDSP1TDP1APEX1
SCHEMBL4884781 0.80 KMT2A (0.63) POLBL3MBTL1CTDSP1TDP1APEX1
SCHEMBL17802794 0.80 ALDH1A1 (0.58) POLBL3MBTL1CTDSP1TDP1APEX1
SCHEMBL13568573 0.80 ALDH1A1 (0.65) POLBL3MBTL1CTDSP1TDP1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11664504-B2 Hematin modified bilirubin oxidase cathode CFD RESEARCH CORPORATION (US) 2023-05-30 US claimed
US-20210384520-A1 HEMATIN MODIFIED BILIRUBIN OXIDASE CATHODE CFD RESEARCH CORPORATION 2021-12-09 US claimed
US-11127966-B2 Hematin modified bilirubin oxidase cathode CFD RESEARCH CORPORATION (US) 2021-09-21 US claimed
US-20150364784-A1 Highly Efficient Enzymatic Bioanodes and Biocathodes STC.UNM (US) 2015-12-17 US claimed
WO-2014110498-A1 HIGHLY EFFICIENT ENZYMATIC BIOANODES AND BIOCATHODES STC.UNM (US) 2014-07-17 WO claimed
EP-3442956-B1 A PROCESS FOR THE PREPARATION OF PYRVINIUM PAMOATE AND CRYSTALLINE FORMS THEREOF URQUIMA SA (ES) 2024-03-27 EP disclosed
CN-117603119-A Preparation of cation free radical-based gene delivery system and application thereof in pancreatic cancer treatment 华南理工大学 2024-02-27 CN disclosed
US-11664504-B2 Hematin modified bilirubin oxidase cathode CFD RESEARCH CORPORATION (US) 2023-05-30 US disclosed
US-20210384520-A1 HEMATIN MODIFIED BILIRUBIN OXIDASE CATHODE CFD RESEARCH CORPORATION 2021-12-09 US disclosed
EP-3645484-B1 METHOD FOR PREPARATION OF ALKYLATED OR FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HETEROGENEOUS COBALT CATALYSIS LONZA SOLUTIONS AG (CH) 2021-11-10 EP disclosed
US-11139500-B2 Alcohol based biofuel cell CFD RESEARCH CORPORATION (US) 2021-10-05 US disclosed
US-11127966-B2 Hematin modified bilirubin oxidase cathode CFD RESEARCH CORPORATION (US) 2021-09-21 US disclosed
US-5554767-A NERVOUS SYSTEM, CARDIOVASCULAR, AND BRAIN DISORDERS WARNER-LAMBERT COMPANY (US) 1996-09-10 US disclosed
US-4273713-A ANTIULCER AND ANTISECRETORY AGENTS STERLING DRUG INC. (US) 1981-06-16 US disclosed
US-4239687-A 4-CARBOXAMIDES, 4-THIOCARBOXAMIDES, 4-NITRILES, ANTISECRETORY, ANTIULCER STERLING DRUG INC. (US) 1980-12-16 US disclosed
US-4140854-A ANTISECRETORY, ANTIULCER STERLING DRUG INC. (US) 1979-02-20 US disclosed
US-4124585-A Rifamycin compounds ARCHIFAR LABORATORI CHIMICO FARMACOLOGICI S.P.A. (IT) 1978-11-07 US disclosed
US-4098797-A ANTISECRETORY, ANTIULCER AGENTS STERLING DRUG INC. (US) 1978-07-04 US disclosed
US-4025347-A Fogged direct-positive silver halide emulsion containing a cyanine dye having an indole or indolenine nucleus substituted with a benzoyl or a phenylsulfonyl group MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-05-24 US disclosed
US-4008250-A ANTISECRETORY, ANTIULCER STERLING DRUG INC. (US) 1977-02-15 US disclosed