Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140835 | 0.77 | CES2 (0.50) | ALDH1A1L3MBTL1LMNAMAPTALOX15 | |
| SCHEMBL23707669 | 0.77 | CES2 (0.50) | ALDH1A1L3MBTL1LMNAMAPTALOX15 | |
| SCHEMBL3756810 | 0.76 | CA1 (0.38) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL22276494 | 0.76 | CA1 (0.38) | ALDH1A1LMNAKDM4ECA1CA2 | |
| SCHEMBL23963013 | 0.76 | ADORA2A (0.37) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL18826578 | 0.76 | CA1 (0.38) | MAPTMYCKDM4EMEN1GAA | |
| SCHEMBL3374566 | 0.73 | ERN1 (0.37) | ALDH1A1LMNAMAPTTSHRKDM4E | |
| SCHEMBL203394 | 0.72 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1LMNAMAPTALOX15 | |
| SCHEMBL3554511 | 0.71 | HTR2C (0.41) | ALDH1A1 | |
| SCHEMBL18456942 | 0.70 | HTR2A (0.36) | ALDH1A1TSHRMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |