Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.66 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.66 |
| ▸ | CDK4 | P11802 | 1/20 | 0.66 |
| ▸ | CCND1 | P24385 | 1/20 | 0.66 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.66 |
| ▸ | GSK3B | P49841 | 8/20 | 0.56 |
| ▸ | PRKCG | P05129 | 5/20 | 0.56 |
| ▸ | PRKCB | P05771 | 3/20 | 0.56 |
| ▸ | PRKCA | P17252 | 3/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.56 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30319849 | 0.79 | CCNE2 (1.00) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL5686048 | 0.79 | CCNE2 (1.00) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL22765422 | 0.74 | PRKCB (0.74) | CDK2GSK3BPRKCGPRKCBPRKCA | |
| SCHEMBL30336889 | 0.74 | PRKCB (0.74) | CDK2GSK3BPRKCGPRKCBPRKCA | |
| SCHEMBL30336971 | 0.74 | PRKCB (0.74) | CDK2GSK3BPRKCGPRKCBPRKCA | |
| SCHEMBL12629162 | 0.74 | PRKCB (0.74) | CDK2GSK3BPRKCGPRKCBPRKCA | |
| SCHEMBL29800011 | 0.74 | PRKCB (0.74) | CDK2GSK3BPRKCGPRKCBPRKCA | |
| SCHEMBL7873226 | 0.74 | CAMK2D (0.67) | CDK2CDK4CCND1PRKCA | |
| SCHEMBL8162775 | 0.73 | PRKACA (0.63) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL14522482 | 0.73 | GSK3B (0.69) | CDK2CCNE2CDK4CCND1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397060-B1 | Maleinimide derivatives and their use as medicines | GOEDECKE AG (DE) | 2001-11-21 | — | — | EP | claimed |