Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641660 | 0.79 | TSHR (0.35) | TP53 | |
| SCHEMBL36899 | 0.79 | ALOX15 (0.32) | LMNA | |
| SCHEMBL8644296 | 0.79 | LMNA (0.40) | LMNATP53 | |
| SCHEMBL8643550 | 0.77 | SOAT1 (0.36) | LMNATP53 | |
| SCHEMBL18643613 | 0.73 | — | — | |
| SCHEMBL2720684 | 0.73 | LMNA (0.41) | LMNATP53 | |
| SCHEMBL197051 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL1790227 | 0.70 | — | — | |
| SCHEMBL2718475 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL9074280 | 0.70 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-B1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-06-20 | — | — | EP | disclosed |