Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455761 | 1.00 | ACHE (0.53) | ACHELMNATSHRALOX12TDP1 | |
| SCHEMBL126082 | 0.88 | ACHE (0.57) | ACHELMNATSHRALOX12TDP1 | |
| SCHEMBL703965 | 0.85 | ALDH1A1 (0.38) | ACHELMNATSHRALOX12TDP1 | |
| SCHEMBL25495182 | 0.82 | MAPT (0.44) | ACHELMNATSHRALOX12TDP1 | |
| Benzene SCHEMBL27873242 | 0.82 | ALDH1A1 (0.40) | ACHELMNATSHRALOX12TDP1 | |
| SCHEMBL38902 | 0.82 | ALDH1A1 (0.40) | ACHELMNATSHRALOX12TDP1 | |
| SCHEMBL12191027 | 0.81 | ACHE (0.50) | ACHELMNATSHRALOX12TDP1 | |
| SCHEMBL28130609 | 0.79 | TSHR (0.37) | ACHELMNATSHRALOX12TDP1 | |
| SCHEMBL3481591 | 0.79 | ACHE (0.48) | ACHELMNATSHRALOX12TDP1 | |
| SCHEMBL24948229 | 0.79 | ACHE (0.41) | ACHELMNATSHRALOX12TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676404-B1 | Oxotitanium complexes useful as asymmetric reaction catalysts particularly for producing beta-hydroxy ketones or alpha-hydroxy carboxylic acid esters | TAKASAGO PERFUMERY CO LTD (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5714624-A | STABLE CATALYST FOR PRODUCTS WITH EXCELLENT OPTICAL ACTIVITY | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-02-03 | — | — | US | disclosed |
| US-5705678-A | Oxotitanium complex, asymmetric hydrogenation catalyst comprising the complex, and process for producing β-hydroxy ketone or α-hydroxy carboxylic acid ester using the complex | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-01-06 | — | — | US | disclosed |
| US-5616751-A | Oxotitanium complex, asymmetric hydrogenation catalyst comprising the complex, and process for producing β-hydroxy ketone or α-hydroxy carboxylic acid ester using the complex | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-04-01 | — | — | US | disclosed |