Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826479 | 0.80 | HDAC11 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29517193 | 0.77 | LMNA (0.46) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL27434544 | 0.77 | LMNA (0.46) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4646095 | 0.75 | KCNN4 (0.47) | KCNN4PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL8432615 | 0.73 | ALDH1A1 (0.47) | PRSS1PPARGPPARAMEN1KMT2A | |
| SCHEMBL8880188 | 0.73 | OPRM1 (0.41) | KCNN4KMT2AKDM4EOPRM1KCNH2 | |
| SCHEMBL27914706 | 0.73 | LMNA (0.42) | KDM4EALDH1A1 | |
| SCHEMBL29184097 | 0.73 | LMNA (0.42) | KDM4EALDH1A1 | |
| SCHEMBL27711277 | 0.73 | LMNA (0.55) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4644357 | 0.71 | KCNN4 (0.50) | KCNN4PRSS1CTSGCTRB1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |