Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704184 | 0.88 | ESR1 (0.54) | ESR1KEAP1NFE2L2KMT2AMEN1 | |
| SCHEMBL7822343 | 0.86 | KEAP1 (0.54) | KEAP1NFE2L2KMT2AALDH1A1MAPT | |
| SCHEMBL9538431 | 0.81 | ESR1 (0.59) | ESR1CA12CA9KEAP1NFE2L2 | |
| SCHEMBL9538438 | 0.81 | ESR1 (0.59) | ESR1CA12CA9KEAP1NFE2L2 | |
| SCHEMBL27591355 | 0.79 | ESR1 (0.60) | ESR1CA12CA9KEAP1NFE2L2 | |
| SCHEMBL7365220 | 0.77 | ESR1 (0.54) | ESR1CA12CA9KEAP1NFE2L2 | |
| SCHEMBL2703652 | 0.76 | PSEN1 (0.57) | ESR1KEAP1NFE2L2KMT2AALDH1A1 | |
| SCHEMBL2703730 | 0.76 | ESR1 (0.40) | ESR1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10798490 | 0.76 | ESR1 (0.49) | ESR1CA12CA9KEAP1NFE2L2 | |
| SCHEMBL2703773 | 0.74 | PSEN1 (0.51) | ESR1KMT2AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |