Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538438 | 1.00 | ESR1 (0.59) | ESR1ALDH1A1CA12CA9TSHR | |
| SCHEMBL7365220 | 0.94 | ESR1 (0.54) | ESR1ALDH1A1CA12CA9TSHR | |
| SCHEMBL8653120 | 0.91 | ESR1 (0.61) | ESR1ALDH1A1TSHRKEAP1NFE2L2 | |
| SCHEMBL10798490 | 0.90 | ESR1 (0.49) | ESR1ALDH1A1CA12CA9TSHR | |
| SCHEMBL27591355 | 0.88 | ESR1 (0.60) | ESR1ALDH1A1CA12CA9TSHR | |
| SCHEMBL5642165 | 0.87 | ALDH1A1 (0.55) | ESR1ALDH1A1CA12CA9TSHR | |
| SCHEMBL8141534 | 0.84 | CA9 (0.56) | ALDH1A1CA12CA9TSHRKEAP1 | |
| SCHEMBL5644407 | 0.82 | OXTR (0.57) | ALDH1A1TSHRKEAP1NFE2L2KMT2A | |
| SCHEMBL7446870 | 0.81 | HTR2C (0.59) | ESR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7826530 | 0.81 | ESR1 (0.55) | ESR1ALDH1A1CA12CA9KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152345-B1 | INTERFERON ADMINISTRATION VEHICLES | INTERFERON SCIENCES, INC a Delaware Corporation (US) | 1993-07-28 | — | — | EP | claimed |