Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 4/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826530 | 0.86 | ESR1 (0.55) | KEAP1NFE2L2MEN1KMT2AALDH1A1 | |
| SCHEMBL5622597 | 0.79 | ALDH1A1 (0.53) | KEAP1NFE2L2LMNAMEN1KMT2A | |
| SCHEMBL5622693 | 0.77 | ESR1 (0.54) | KEAP1NFE2L2TP53LMNAALDH1A1 | |
| SCHEMBL5622125 | 0.77 | PSEN1 (0.60) | KEAP1NFE2L2LMNAMEN1KMT2A | |
| SCHEMBL7821400 | 0.76 | LMNA (0.72) | KEAP1NFE2L2TP53LMNAMEN1 | |
| SCHEMBL2703773 | 0.76 | PSEN1 (0.51) | TP53LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL2704184 | 0.74 | ESR1 (0.54) | KEAP1NFE2L2LMNAMEN1KMT2A | |
| SCHEMBL2703652 | 0.74 | PSEN1 (0.57) | KEAP1NFE2L2MEN1KMT2AALDH1A1 | |
| SCHEMBL2118315 | 0.73 | PSEN1 (0.57) | TP53LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL5644407 | 0.73 | OXTR (0.57) | KEAP1NFE2L2TP53LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |