Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.52 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.52 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826920 | 0.82 | SLC9A1 (0.54) | SLC9A1SLC9A3SLC9A2LMNAGAA | |
| SCHEMBL9392969 | 0.78 | SLC9A1 (0.48) | SLC9A1SLC9A3SLC9A2LMNAGAA | |
| SCHEMBL7825774 | 0.76 | LMNA (0.57) | SLC9A1SLC9A3SLC9A2LMNAGAA | |
| SCHEMBL27401335 | 0.71 | SLC9A1 (0.59) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8704441 | 0.71 | SLC9A1 (0.59) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL7822660 | 0.71 | SLC9A1 (0.59) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL7823230 | 0.71 | SLC9A1 (0.56) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8447084 | 0.69 | SLC9A1 (0.64) | SLC9A1SLC9A3SLC9A2 | |
| Guanidine SCHEMBL8704984 | 0.68 | KMT2A (0.38) | SLC9A1SLC9A3SLC9A2LMNAGAA | |
| Eniporide SCHEMBL29359307 | 0.68 | SLC9A1 (1.00) | SLC9A1SLC9A3SLC9A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699185-B1 | GUANIDINE DERIVATIVES AS INHIBITORS OF Na+ /H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0699185-A1 | GUANIDINE DERIVATIVES AS INHIBITORS OF Na+ /H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-03-06 | — | — | EP | disclosed |