Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826963 | 1.00 | TTR (0.41) | TTRAPPPTPN1EPHX2KDM4E | |
| SCHEMBL7822903 | 0.88 | IAPP (0.38) | APPJAK2FDPSCCNB2CDK1 | |
| SCHEMBL7822589 | 0.84 | F3 (0.48) | ALDH1A1MAPTKMT2APADI4 | |
| SCHEMBL7828906 | 0.81 | SRC (0.35) | KDM4ESMN1; SMN2MAPTGAAKMT2A | |
| SCHEMBL7815811 | 0.81 | NPC1 (0.33) | SMN1; SMN2MAPTKMT2APADI4HDAC3 | |
| SCHEMBL7815807 | 0.81 | NPC1 (0.33) | SMN1; SMN2MAPTKMT2APADI4HDAC3 | |
| SCHEMBL7829829 | 0.80 | CCNB2 (0.33) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL7825038 | 0.80 | CCNB2 (0.33) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL7825041 | 0.80 | CCNB2 (0.33) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL7830758 | 0.79 | MMP1 (0.48) | KDM4EALDH1A1SMN1; SMN2MAPTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |