Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | USP20 | Q9Y2K6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825041 | 1.00 | CCNB2 (0.33) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL7825038 | 1.00 | CCNB2 (0.33) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL7825535 | 0.83 | KIF11 (0.43) | GSK3B | |
| SCHEMBL8073292 | 0.82 | IP6K1 (0.41) | CDK1 | |
| SCHEMBL8073308 | 0.82 | IP6K1 (0.41) | CDK1 | |
| SCHEMBL7825711 | 0.82 | CCNB2 (0.37) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL7822903 | 0.81 | IAPP (0.38) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL7826959 | 0.80 | TTR (0.41) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL7826963 | 0.80 | TTR (0.41) | CCNB2CDK1CCNB1GSK3BCDK5 | |
| SCHEMBL8069062 | 0.79 | IP6K1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |