Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820722 | 0.81 | CYP1A2 (0.57) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL7821493 | 0.79 | HPGD (0.58) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL7823201 | 0.79 | TAS1R3 (0.55) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL11284668 | 0.78 | PDCD1 (0.64) | PDCD1CD274KDM4EALDH1A1HPGD | |
| SCHEMBL29360280 | 0.77 | MEN1 (0.57) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL42567 | 0.77 | MEN1 (0.57) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL786246 | 0.76 | PDCD1 (0.81) | PDCD1CD274KDM4EALDH1A1HPGD | |
| SCHEMBL2761484 | 0.76 | GAA (0.55) | KDM4EALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL11248349 | 0.75 | SMN1; SMN2 (0.52) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10481401 | 0.74 | KMT2A (0.60) | PDCD1CD274KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |