Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820722 | 0.84 | CYP1A2 (0.57) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7821493 | 0.81 | HPGD (0.58) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL11248349 | 0.81 | SMN1; SMN2 (0.52) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL42567 | 0.79 | MEN1 (0.57) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29360280 | 0.79 | MEN1 (0.57) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7827337 | 0.79 | PDCD1 (0.55) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2761484 | 0.78 | GAA (0.55) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12189441 | 0.77 | L3MBTL1 (0.56) | RAB9ASMN1; SMN2LMNAMAPK1ALDH1A1 | |
| SCHEMBL7824641 | 0.76 | MAPT (0.63) | SMN1; SMN2MEN1KMT2ATP53LMNA | |
| SCHEMBL29429740 | 0.74 | RAB9A (0.86) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |