Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360280 | 0.89 | MEN1 (0.57) | CYP1A2HPGDCYP2C19NPC1RAB9A | |
| SCHEMBL42567 | 0.89 | MEN1 (0.57) | CYP1A2HPGDCYP2C19NPC1RAB9A | |
| SCHEMBL7824641 | 0.84 | MAPT (0.63) | CYP1A2HPGDCYP2C19ALDH1A1MEN1 | |
| SCHEMBL7823201 | 0.84 | TAS1R3 (0.55) | NPC1RAB9AP4HTMALDH1A1MEN1 | |
| SCHEMBL7821493 | 0.84 | HPGD (0.58) | CYP1A2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL7827337 | 0.81 | PDCD1 (0.55) | HPGDNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL2761484 | 0.81 | GAA (0.55) | CYP1A2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL11248349 | 0.80 | SMN1; SMN2 (0.52) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12189441 | 0.79 | L3MBTL1 (0.56) | RAB9AL3MBTL1ALDH1A1ATMMAPT | |
| SCHEMBL7534495 | 0.78 | CYP1A2 (0.51) | CYP1A2HPGDCYP2C19NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |