SCHEMBL7825538

SCHEMBL7825538

COc1cccc2c1C(=N)NC2(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.39
KMT2A Q03164 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
CA12 O43570 1/20 0.35
CA4 P22748 1/20 0.35
CA14 Q9ULX7 1/20 0.35
TOP1 P11387 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
TXNRD1 Q16881 1/20 0.35
TXNRD3 Q86VQ6 1/20 0.35
TXNRD2 Q9NNW7 1/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7827148 0.86 PDK2 (0.35) PDK2KMT2ACA1CA2CA7
SCHEMBL7824104 0.85 PDK2 (0.43) PDK2KMT2AKDM4EALDH1A1TP53
SCHEMBL7823198 0.84 PDK2 (0.33) PDK2
SCHEMBL7816167 0.83 MAPK1 (0.36) KMT2AALDH1A1LMNATP53MAPT
SCHEMBL7828048 0.79 CES1 (0.33) PDK2
SCHEMBL7826806 0.78 PRKCA (0.42) KMT2ALMNATP53CYP3A4MAPT
SCHEMBL7830779 0.78 PRKCA (0.42) KMT2ALMNATP53CYP3A4MAPT
SCHEMBL7828883 0.77 CA2 (0.33) CA2
SCHEMBL8921478 0.76 TXNRD1 (0.42) PDK2KMT2ACA1CA2CA7
SCHEMBL7831463 0.76 CA1 (0.36) PDK2KMT2ACA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed