SCHEMBL7829948

SCHEMBL7829948

CCCCOc1cccc2c1C(=N)NC2(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
PRKCA P17252 6/20 0.36
MCHR1 Q99705 1/20 0.36
CYP19A1 P11511 1/20 0.35
TP53 P04637 2/20 0.35
PDK2 Q15119 1/20 0.34
ELANE P08246 1/20 0.33
TLR8 Q9NR97 1/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7826806 0.95 PRKCA (0.42) CYP1A2CYP2C9CYP2C19PRKCAMCHR1
SCHEMBL7830779 0.95 PRKCA (0.42) CYP1A2CYP2C9CYP2C19PRKCAMCHR1
SCHEMBL7827488 0.93 MCHR1 (0.35) CYP1A2CYP2C9CYP2C19PRKCAMCHR1
SCHEMBL7822891 0.89 CYP1A2 (0.38) CYP1A2CYP2C9CYP2C19PRKCAMCHR1
SCHEMBL7824104 0.88 PDK2 (0.43) TP53PDK2TSHR
SCHEMBL7827899 0.84 PRKCA (0.40) CYP1A2CYP2C9CYP2C19PRKCAMCHR1
SCHEMBL7828606 0.84 PRKCA (0.40) CYP1A2CYP2C9CYP2C19PRKCAMCHR1
SCHEMBL7827247 0.82 PDK2 (0.36) CYP1A2CYP2C19PRKCAMCHR1PDK2
SCHEMBL7823190 0.81 CYP1A2 (0.40) CYP1A2CYP2C9CYP2C19MCHR1CYP19A1
SCHEMBL7825538 0.81 PDK2 (0.39) TP53PDK2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed