Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PMM2 | O15305 | 1/20 | 0.51 |
| ▸ | MPI | P34949 | 1/20 | 0.51 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828377 | 0.84 | CA12 (0.48) | AOC2TP53L3MBTL1GAAALDH1A1 | |
| SCHEMBL2357788 | 0.84 | CA12 (0.48) | AOC2TP53L3MBTL1GAAALDH1A1 | |
| SCHEMBL5868847 | 0.83 | TP53 (0.67) | TP53L3MBTL1GAAALDH1A1HPGD | |
| SCHEMBL27382417 | 0.83 | TP53 (0.51) | AOC2TP53L3MBTL1GAAALDH1A1 | |
| SCHEMBL27383697 | 0.83 | TP53 (0.51) | AOC2TP53L3MBTL1GAAALDH1A1 | |
| SCHEMBL7830321 | 0.82 | SMN1; SMN2 (0.56) | AOC2ALDH1A1CYP4F2CYP4A11LMNA | |
| SCHEMBL18979346 | 0.82 | TP53 (0.50) | AOC2TP53L3MBTL1GAAALDH1A1 | |
| SCHEMBL27403228 | 0.82 | TP53 (0.50) | TP53L3MBTL1GAAALDH1A1HPGD | |
| SCHEMBL27400146 | 0.82 | TP53 (0.50) | AOC2TP53L3MBTL1GAAALDH1A1 | |
| SCHEMBL27383013 | 0.82 | TP53 (0.50) | TP53GAAALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685713-B2 | Small molecule SHC blockers used for treating liver disease and metabolic disease | BUTO CORPORATION (US) | 2023-06-27 | — | — | US | disclosed |
| US-11685713-B2 | Small molecule SHC blockers used for treating liver disease and metabolic disease | BUTO CORPORATION (US) | 2023-06-27 | — | — | US | disclosed |
| US-20230002317-A1 | NOVEL SMALL MOLECULE SHC BLOCKERS USED FOR TREATING LIVER DISEASE AND METABOLIC DISEASE | BUTO CORPORATION | 2023-01-05 | — | — | US | disclosed |
| US-9758485-B2 | Compounds for controlling arthropods | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-09-12 | — | — | US | disclosed |
| US-20160297765-A1 | NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20160278379-A1 | NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-09-29 | — | — | US | disclosed |
| CN-1080257-C | Guanidine derivatives as inhibitors of Na+/H+ exchange in cells | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-03-06 | — | — | CN | disclosed |
| EP-0699185-B1 | GUANIDINE DERIVATIVES AS INHIBITORS OF Na+ /H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |
| CN-1123545-A | Guanidine derivatives as inhibitors of Na+/H+ exchange in cells | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-05-29 | — | — | CN | disclosed |
| EP-0699185-A1 | GUANIDINE DERIVATIVES AS INHIBITORS OF Na+ /H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994026709-A1 | GUANIDINE DERIVATIVES AS INHIBITORS OF Na+/H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685713-B2 | Small molecule SHC blockers used for treating liver disease and metabolic disease | SHC1, GPR119, GYS2 | AOC2 4469/4885TP53 2758/4885L3MBTL1 3672/4885 |
| US-20230002317-A1 | NOVEL SMALL MOLECULE SHC BLOCKERS USED FOR TREATING LIVER DISEASE AND METABOLIC DISEASE | GPR119, SHC1, GLS2 | AOC2 4279/4885TP53 3081/4885L3MBTL1 3463/4885 |
| US-20160278379-A1 | NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS | CYP4X1, CYP4B1, SERPINB6 | AOC2 333/4885TP53 4832/4885L3MBTL1 204/4885 |
| US-20160297765-A1 | NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS | CYP4X1, CYP4B1, SERPINB6 | AOC2 333/4885TP53 4832/4885L3MBTL1 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.