Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 4/20 | 0.42 |
| ▸ | RORA | P35398 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.42 |
| ▸ | DTYMK | P23919 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942455 | 0.80 | MAPT (0.49) | HPDMAPTLMNAHTTMEN1 | |
| SCHEMBL8492000 | 0.80 | MAPT (0.49) | HPDMAPTLMNAHTTMEN1 | |
| SCHEMBL442397 | 0.80 | HPD (0.60) | HPDMAPTLMNAHTTMEN1 | |
| Ammonia Solution, Strong SCHEMBL28953061 | 0.79 | HPD (0.59) | HPDMAPTLMNAHTTMEN1 | |
| Hydrochloric Acid SCHEMBL11776053 | 0.79 | HPD (0.59) | HPDMAPTLMNAHTTMEN1 | |
| SCHEMBL10680778 | 0.78 | CYP1A2 (0.58) | HPDMAPTLMNAHTTRORC | |
| SCHEMBL10685921 | 0.77 | CYP1A2 (0.43) | MAPTLMNARORCRORAMEN1 | |
| SCHEMBL7828119 | 0.74 | HPD (0.42) | HPDMAPTLMNARORCRORA | |
| SCHEMBL107505 | 0.74 | ALDH1A1 (0.51) | MAPTLMNAHTTRORCRORA | |
| SCHEMBL700691 | 0.74 | NPC1 (0.56) | HPDMAPTLMNAHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |