Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492159 | 0.75 | HPD (0.52) | HPDMAPTMEN1KMT2APOLB | |
| Glycolic Acid SCHEMBL7828115 | 0.74 | HPD (0.46) | HPDMAPTMEN1KMT2ALMNA | |
| SCHEMBL8787361 | 0.70 | HPD (0.49) | HPDMAPTMEN1KMT2ALMNA | |
| SCHEMBL107505 | 0.70 | ALDH1A1 (0.51) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL22749351 | 0.69 | CFTR (0.58) | HPDMAPTMEN1KMT2ALMNA | |
| SCHEMBL5841692 | 0.69 | HPD (0.54) | HPDMAPTMEN1KMT2ALMNA | |
| SCHEMBL10680778 | 0.69 | CYP1A2 (0.58) | HPDMAPTMEN1KMT2ALMNA | |
| SCHEMBL30959714 | 0.68 | CFTR (0.60) | HPDMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL1450704 | 0.68 | CFTR (0.60) | HPDMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL10685921 | 0.68 | CYP1A2 (0.43) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |