Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5605710 | 0.94 | NQO1 (0.58) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL9155582 | 0.79 | NQO1 (0.82) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL18417193 | 0.79 | NQO1 (0.82) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL5833291 | 0.79 | NQO1 (0.82) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL7821014 | 0.79 | ESR2 (0.54) | NPC1CYP1A2 | |
| SCHEMBL2154536 | 0.78 | NQO1 (0.64) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL7705345 | 0.77 | ESR1 (0.35) | — | |
| SCHEMBL31402687 | 0.76 | NQO1 (0.61) | NQO1PARP10PRSS1PRSS2PRSS3 | |
| SCHEMBL7828145 | 0.75 | FFAR1 (0.46) | NQO1PARP10LTA4HTDP1TSHR | |
| SCHEMBL17061036 | 0.75 | NQO1 (0.58) | NQO1PARP10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |