SCHEMBL7705345

SCHEMBL7705345

O=[PH](O)c1ccc(-c2ccc([PH](=O)O)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.35
ESR2 Q92731 1/20 0.35
ALOX5 P09917 1/20 0.31
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21112089 0.90
SCHEMBL916573 0.89 ESR1 (0.55) ESR1ESR2ALOX5
SCHEMBL755658 0.89 MMP3 (0.46) ALOX5
SCHEMBL5530567 0.83 BCL2L1 (0.54)
SCHEMBL7821014 0.82 ESR2 (0.54) ESR2APP
SCHEMBL11660419 0.82 KMO (0.48) ESR1ALOX5APP
Biphenyl SCHEMBL9807554 0.80 ALDH1A1 (0.47)
Sulfur Dioxide SCHEMBL28692326 0.80 MMP3 (0.37)
SCHEMBL915063 0.79 LMNA (0.47) ESR1ESR2
SCHEMBL7828144 0.77 NQO1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002338584-A METHOD FOR SEPARATION AND PURIFICATION OF BIPHENYLDIPHOSPHINIC ACID TORAY IND INC 2002-11-27 JP disclosed